ova peptide siinfekl ovalbumin-derived peptide with sequence SIINFEKL - SIINFEKL peptide ovalbumin-derived peptide with sequence SIINFEKL Understanding the Ova Peptide SIINFEKL: A Key Player in Immunological Research

SIINFEKLantibody The ova peptide SIINFEKL is a significant biomolecule frequently referenced in immunological research, particularly in the study of T cell responses and antigen presentation. This octameric peptide, derived from chicken ovalbumin (OVA), holds a prominent position due to its well-defined interactions with the immune system. The precise sequence, SIINFEKL, is recognized as a class I (Kb)-restricted peptide epitope of OVA, meaning it is presented by the major histocompatibility complex (MHC) class I molecule, H-2Kb. This specific interaction is crucial for activating certain types of immune cells, making SIINFEKL an invaluable tool for researchers.

The significance of the ova peptide SIINFEKL lies in its consistent ability to elicit a predictable immune response. It is routinely used to stimulate ovalbumin-specific T cells, providing a reliable model for investigating T cell immunology. This peptide's role extends to testing new vaccine adjuvants, assessing their efficacy in inducing a robust T cell response. Furthermore, SIINFEKL is employed in methods to monitor antigen presentation, a fundamental process where immune cells display fragments of antigens to other immune cells. Researchers often utilize specialized reagents like the 25-D1.作者：M Kamalov·2019·被引用次数：16—Here we show that the well-known ovalbumin epitope SIINFEKL that isroutinely used to stimulate ovalbumin-specific T cellsand to test new vaccine adjuvants ...16 monoclonal antibody, which specifically detects the ovalbumin-derived peptide SIINFEKL when bound to H-2Kb molecules. This antibody allows for the quantifiable study of antigen-MHC complexes, offering insights into the dynamics of immune surveillance.作者：HN Eisen·2012·被引用次数：64—The peptides tested wereSIINFEKL(often referred to as. OVA257–264 but here referred to simply as OVA) and SIYR-. YYGL (termed SIY). OVA is ...

Detailed insights into the ova peptide SIINFEKL are available through various scientific resources. For instance, its molecular formula is identified as C45H74N10O13, with a molecular weight of approximately 963.Ova (257-264) - SIINFEKL cytotoxic T lymphocytes1 g/mol.OVA (257-264) Chicken Ovalbumin Peptide - SIINFEKL This precisely defined structure facilitates its use in experiments where molecular characteristics are paramount. In the realm of research, SIINFEKL is also known by its CAS number 138831-86-4.

The ova peptide SIINFEKL is not only studied in its native form but also in various modified versions. For example, the OVA G4 peptide is a SIINFEKL variant or SIINFEKL Cariant, meaning it has undergone specific amino acid substitutions that can affect its affinity for MHC-I or T cell receptors (TCR)Findova peptide – siinfekl s7951and related products for scientific research at MilliporeSigma.. Another noted OVA peptide SIINFEKL variant is the G4 peptide (SIIGFEKL), which distinguishes itself from the primary OVA (257-264) sequence. These peptides and their variants allow researchers to explore the nuances of epitope recognition and immune activation.

Applications of SIINFEKL are diverse and impactful. It is used to stimulate T cells in PBMCs (peripheral blood mononuclear cells), a common practice in research settings.OVA Peptide (257-264) | 138831-86-4 | POV-3659-PI The SIINFEKL peptide is also instrumental in quantifying peptide epitope specificity and effector cells that release Interferon-gamma (IFN-γ) using assays like ELISPOT. Beyond T cell research, the ova peptide SIINFEKL is commonly used to stimulate allergic reactions in allergy models and as a model antigen to study T cell responses in the context of vaccination.

When sourcing this critical research material, specific identifiers are importantA SIINFEKL-Based System to Measure MHC Class I Antigen .... Products such as Ova peptide – siinfekl s7951 are commercially available for scientific research. The availability of OVA 257-264 (SIINFEKL), often described as an octameric peptide from ovalbumin, as a class I (Kb)-restricted peptide epitope of OVA, underscores its accessibility for laboratory work. Furthermore, two standard OVA peptides for detection use are commonly available, including the H-2Kb-restricted OVA class I epitope (which is SIINFEKL) and an I-A(d)-restricted OVA class II epitope. When referring to OVA peptides, it's essential to clarify the specific epitope being discussed, such as the well-characterized OVA257-264 octapeptide with the amino acid sequence SIINFEKLbiotin-SIINFEKL [LT8220] - 0.00.

The Search intent behind queries related to ova peptide SIINFEKL reflects a deep interest in its properties, applications, and availability for immunological studies.OVA(257-264) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb. Whether researchers are looking for SIINFEKL tetramers, SIINFEKL antibodies, or simply understanding what is SIINFEKL, the underlying goal is to leverage this peptide for advancing scientific knowledge in immunology and related fieldsOVA (257-264) (H-2Kb) | 1 mg | EP01994_1. The consistent presence of OVA, peptide, and ova peptide SIINFEKL in related searches and descriptions highlights its central role in this area of scientific inquiry.