Ot iipeptide The OVA peptide 323-339, a specific fragment derived from chicken ovalbumin (OVA), holds considerable importance in the field of immunology, particularly in the study of T cell and B cell epitopes. This prominent antigen peptide derived from chicken ovalbumin protein plays a crucial role in the generation and development of immediate hypersensitivity responses, making it a valuable tool for researchers investigating allergies and immune system function.
Derived from the ovalbumin protein, the OVA (323-339) peptide has a well-defined amino acid sequence: Ile-Ser-Gln-Ala-Val-His-Ala-Ala-His-Ala-Glu-Ile-Asn-Glu-Ala-Gly-Arg. This sequence, often referred to as OVA peptide 323-339, has been extensively studied for its immunogenic properties.OVA (323-339) It is recognized as a key epitope, meaning it is the specific part of the antigen that triggers an immune response.
A significant aspect of OVA peptide 323-339 is its interaction with MHC class II molecules. Specifically, it is an H-2b-restricted OVA class II and H2-IAd epitope. This binding capability allows the OVA peptide 323-339 to be presented to CD4+ T cells by antigen-presenting cells, such as dendritic cells.Small volumes ofOVA Peptide (323-339) active peptidevial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. Studies have shown that this peptide is responsible for a substantial portion, reportedly 25-35%, of the T-cell response to intact OVA in certain animal models, such as the BALB/c mouse.OVA Peptide (323-339) | 92915-79-2 This highlights its critical role in orchestrating the adaptive immune responseOVA Peptide (323-339) | Kb-Restricted Peptide Epitope.
Furthermore, OVA Peptide (323-339) functions as a B cell epitope as well, capable of being recognized by IgE antibodiesOVA Peptide (323-339) - MedChem Express. This makes it particularly relevant in the study of allergic reactions, where IgE antibodies play a central role in initiating hypersensitivity responses. The ability of OVA peptide 323-339 to elicit responses from both T and B cells underscores its significance in allergic research and in establishing animal models for studying immediate hypersensitivity.OVA(323-339) (Plasmid #190005). Print. Purpose. Piggybac construct for constitutive expression of mCherry and Chicken Ovalbumin OVA323-339 peptide fusion. The OVA 323-339 peptide is therefore an allergenic and antigenic epitope of the ovalbumin proteinThis is anOVA (323-339) peptide fragment. An H-2b-restricted OVA class II ... OVA (323-339). 8.00 0 %. Check your price. Cat.Number : AS-27024 ....
Researchers utilize OVA peptide 323-339 in various experimental settings.OVA Peptide (323-339) active peptide It is commonly employed to induce immune responses in animal models, such as the experimental autoimmune encephalomyelitis (EAE) model, or to investigate immune checkpoint activity. The peptide can be synthesized and modified, for instance, being available as a Cy3-Ova (323-339) or (TAMRA labeled) version for fluorescent tracking in biological assays. The availability of this active peptide in various forms facilitates diverse research applications.
The OVA peptide (323-339), with its CAS number 92915-79-2, is a widely available reagent for scientific research, offered by numerous chemical and biological supply companies. Its precise amino acid sequence and immunogenic characteristics make it an indispensable tool for understanding the complexities of ovalbumin protein Ova (323-339) recognition and the development of immune-mediated conditions. Whether investigating human dendritic cells' recognition of the ova peptide sequence (323-339) in non-allergic individuals or developing therapeutic strategies for allergies, the OVA peptide 323-339 remains a cornerstone of immunological investigation.OVA Peptide (323-339) represents a T and B cell epitope of Ovalbumin (Ova), which is important in the generation and development of immediate hypersensitivity ... The term Ova in this context refers to the ovalbumin proteinGenscript Corporation OVA Peptide (323-339). Understanding the role of specific Ova peptides like this fragment is crucial for advancing our knowledge of immune responses.
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